The first company in China to hold Class II & III of registration certificates for both dental implants and personalized abutments

广东中科安齿生物科技有限公司（简称“中科安齿”）是由中科院孵化的一家具有国家二类、三类医疗器械资质的省级专精特新企业，是中国首家同时拥有牙种植体和个性化基台三类注册证的企业，2023年，成为广东省唯一入选国家集采的本土企业，是甲类中标单位；2024年，与国家一级央企通用技术宝石花医疗签署全面战略合作协议，成为其国产医疗器械的独家供应商。 公司产品已获准4个三类、多个二类国家医疗器械注册证。目前已获得知名股权投资机构的八轮风险投资，是上市科创板的后备50家企业之一。 公司主要研发如下产品及技术： （1）达到世界一流水平的通用型牙科种植体； （2）基于影像技术和3D打印技术的个性化牙科种植体； （3）研发个性化牙科骨粉用支撑钛网，为大面积骨缺损情况下的口腔种植手术提供引导骨再生的新治疗方案； （4）微米-纳米复合亲水性表面处理技术，并以此建造自主知识产权的医疗器械表面处理生产线； （5）提供基于扫描，影像等技术，以修复为导向、以精准为核心，自动匹配最优种植方案的数字化种植技术，以应对各种口腔种植疑难杂症； （6）把3D打印相关技术融入癌症修复、创伤救治和整容整形等诸多领域，开发个性化精准医疗修复材料； （7）开发基于口腔检查的人工智能健康护航系统，由硬件、软件及应用平台三部分组成，通过AI技术对口腔健康数据进行深入分析，做出健 康管理； We are actively seeking potential partners to expand our sales channels, including distributors worldwide, as well as public and private hospitals. We are also open to exploring joint venture opportunities. **CAS Angel Biotechnology Co., Ltd.** (广东中科安齿生物科技有限公司, abbreviated as **“CAS Angel”**) is a **provincial-level “Specialized, Refined, Differentiated, and Innovative” enterprise** incubated by the **Chinese Academy of Sciences (CAS)**. The company holds national qualifications for both **Class II and Class III medical devices**, and is the **first enterprise in China** to simultaneously obtain **Class III registration certificates** for **dental implants** and **customized abutments**. To date, the company has obtained **four Class III** and **multiple Class II** national medical device registration certificates. CAS Angel has completed **eight rounds of venture capital financing** from prominent investment institutions and is listed as one of the **Top 50 reserve enterprises for a STAR Market IPO**. CAS Angel focuses on the research and development of the following core products and technologies: 1. **World-class universal dental implants** 2. **Customized dental implants** based on **imaging technology and 3D printing** 3. **Titanium mesh supports** for personalized dental bone grafting materials, providing new **guided bone regeneration (GBR)** solutions for **large-area bone defects** during oral implant surgeries 4. **Micron-nano composite hydrophilic surface treatment technology**, and the development of a **self-owned IP production line** for surface treatment of medical devices 5. **Digital implantology solutions** based on scanning and imaging, which are **restoration-oriented** and **precision-driven**, capable of **automatically matching optimal implant strategies** for various complex cases 6. Integration of **3D printing technologies** into **cancer reconstruction, trauma recovery, and cosmetic surgery**, to develop **personalized precision medical restoration materials** 7. An **AI-based oral health monitoring system**, comprising **hardware, software, and an application platform**, which uses **artificial intelligence to analyze oral health data** and provide intelligent health management services